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Osteoarthritis of the Knee 

Osteoarthritis is the most common form of arthritis in the knee. It is a degenerative, "wear-and-tear" type of arthritis that occurs most often in people 50 years of age and older, although it may occur in younger people, too. In osteoarthritis, the cartilage in the knee joint gradually wears away. As the cartilage wears away, it becomes frayed and rough, and the protective space between the bones decreases. This can result in bone rubbing on bone and produce painful bone spurs.

Osteoarthritis of the Knee Research Study

Are you a male or female aged 40 and older?

Have Grade 2 or 3 primary osteoarthritis of the target knee?

Have Osteoarthritis of the knee?

Are you willing to make study visits?

If you are willing to participate in this study or need more information about the study please call us at:​



  • The joint may become stiff and swollen, making it difficult to bend and straighten the knee

  • Pain and swelling may be worse in the morning, or after sitting or resting

  • Vigorous activity may cause pain to flare up

  • Loose fragments of cartilage and other tissue can interfere with the smooth motion of joints. The knee may "lock" or "stick" during movement. It may creak, click, snap or make a grinding noise (crepitus

  • Pain may cause a feeling of weakness or buckling in the knee.

  • Many people with arthritis note increased joint pain with changes in the weather.

Osteoarthritis of the Knee
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